Cosmetic Regulatory Intelligence

Structured Safety Intelligence for cosmetic formulation. Query 38,411 NOAEL records, 68,540 pre-calculated Margin of Safety values, and 25,157 jurisdictional regulatory opinions across 12 markets (EU, US FDA, Korea MFDS, Japan MHLW, ASEAN, Saudi SFDA, Canada, Australia, ECHA SVHC, CA Prop 65, CA TFCA, WA TFCA). Tools: check_ingredient, check_formula, search_ingredients, calculate_mos. v1.1.0: every ingredient response includes full jurisdictional_profile across all 12 jurisdictions.

该来源不提供完整文件导出（国内平台多为平台内托管），仅存元数据与原链

接入信息

传输形态: http
鉴权方式: 鉴权未知
端点: https://cosmetic-regulatory--twohalves.run.tools

鉴权方式未标注，请核对官方文档后再接入——不要直接使用以下片段

{
  "mcpServers": {
    "Cosmetic Regulatory Intelligence": {
      "url": "https://cosmetic-regulatory--twohalves.run.tools"
    }
  }
}

能力清单

工具	说明
check_ingredient	Check a cosmetic ingredient by common name, INCI name, or CAS number. Use when the user asks whether an ingredient such as retinol, niacinamide, phenoxyethanol, or titanium dioxide is safe, restricted, banned, sensitizing, endocrine-active, SVHC-listed, or acceptable for cosmetic use. Do not use for full formula scans, exposure-only MoS math, food additive questions, pharmaceutical actives outside cosmetic use, or broad ingredient discovery. The response includes matched identifiers, SCCS/CIR safety evidence, jurisdictional restrictions, NOAEL data, sensitization records, SVHC flags, and any pre-calculated Margin of Safety values.
check_formula	Scan a cosmetic formula INCI list for ingredient-level regulatory and safety risk. Use when the user pastes a product label, asks to screen a formula, requests CPSR-style triage, or wants EU/US/multi-jurisdiction flags across many ingredients. Do not use for a single ingredient lookup, a free-text category search, or a custom SCCS Margin of Safety calculation for one ingredient concentration. The response includes normalized ingredient matches, restricted or banned substances, jurisdiction flags, safety notes, and an overall LOW, MODERATE, or HIGH formula risk assessment.
search_ingredients	Search cosmetic ingredient records by partial name, function, category, or concept. Use when the user needs candidate INCI names for terms like sunscreen, preservative, retinoid, fragrance allergen, humectant, or hyaluronic acid before choosing a specific record. Do not use when the user has an exact INCI/CAS and needs restrictions, NOAEL, or MoS data; use check_ingredient for that. The response includes matching ingredient names, functions or categories where available, safety scores, and regulatory status hints.
calculate_mos	Calculate cosmetic Margin of Safety from ingredient concentration and product type. Use when the user provides an ingredient, percentage, and product format and asks for SCCS-style MoS, SED, safe concentration, or exposure assessment. Do not use for regulatory lookup alone, formula batch screening, food/pharma exposure questions, or when concentration is unknown. The response includes NOAEL source, systemic exposure dose, dermal absorption basis, product exposure assumptions, MoS value, and pass/fail threshold assessment.

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